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While theres no direct evidence that IGF-1 causes cancer, it can theoretically accelerate the growth of existing or dormant tumors , especially in hormone-sensitive tissues like the breast, prostate, or colon

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Those results demonstrate that regulation of central metabolism is responsible for the observed robustness of cytosolic NADP redox status, which is itself a prerequisite for the previously-described robustness of the glutathione redox status

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Research on growth hormone replacement shows that when GH levels are restored gently and monitored, the therapy is well tolerated with a low incidence of complications

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